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. 2020 Oct 23;71(7):1760-1763.
doi: 10.1093/cid/ciaa007.

High Rates of Influenza-Associated Invasive Pulmonary Aspergillosis May Not Be Universal: A Retrospective Cohort Study from Alberta, Canada

Ilan S Schwartz  1 , Daniel Z P Friedman  1 , Lori Zapernick  1 , Tanis C Dingle  2 , Nelson Lee  1 , Wendy Sligl  1   3 , Nathan Zelyas  2 , Stephanie W Smith  1
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High Rates of Influenza-Associated Invasive Pulmonary Aspergillosis May Not Be Universal: A Retrospective Cohort Study from Alberta, Canada

Ilan S Schwartz et al. Clin Infect Dis. .

Abstract

From 2014-2019, invasive pulmonary aspergillosis complicated 7.2% (0-23.1% in different influenza seasons) of cases of influenza-associated respiratory failure in Edmonton, Alberta. Disease outcomes ranged from survival without therapy to death despite antifungals. Clinician vigilance, longitudinal local surveillance, and refined criteria to identify patients requiring therapy are needed.

Keywords: Aspergillus; aspergillosis; emerging infections; influenza; intensive care.

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