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. 2019 Dec 2:33:100629.
doi: 10.1016/j.nmni.2019.100629. eCollection 2020 Jan.

Co-circulation of dengue virus type 3-genotype I and type 2-Cosmopolitan genotype in 2018 outbreak in Dhaka, Bangladesh

F U Ahmad  1 , S K Paul  1 , M S Aung  2 , R Mazid  1 , M Alam  1 , S Ahmed  1 , N Haque  1 , M A Hossain  3 , S Paul  4 , R Sharmin  5 , N Kobayashi  2
Affiliations

Co-circulation of dengue virus type 3-genotype I and type 2-Cosmopolitan genotype in 2018 outbreak in Dhaka, Bangladesh

F U Ahmad et al. New Microbes New Infect. .

Abstract

Dengue virus (DENV) that caused an outbreak in Dhaka, Bangladesh during 2018 was analysed phylogenetically. DENV samples were classified into type 2-Cosmopolitan genotype (54%) and type 3-genotype I (46%), indicating co-circulation of two DENV types and resurgence of type 3 associated with genotype replacement.

Keywords: Bangladesh; Dhaka; dengue virus; resurgence; type 3.

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Figures

Fig. 1
Fig. 1
Phylogenetic dendrogram of partial C-prM gene of dengue virus type 2 (DENV-2) (a) and DENV-3 (b) causing the 2018 outbreak in Dhaka, Bangladesh (closed circle), and those from other diverse geographical locations, constructed by maximum likelihood method using the MEGA.7 software package. The tree was statistically supported by bootstrapping with 1000 replicates, and genetic distances were calculated using the Kimura two-parameter model. The variation scale is described at the bottom. Percentage bootstrap support is indicated by the values at each node (values <80 are omitted). Black square indicates a DENV-2 strain that was imported from Bangladesh to China (a) and DENV-3 strains detected in Bangladesh in 2002 (b). Genotypes of DENV-2 and DENV-3 are shown at right.
Fig. 1
Fig. 1
Phylogenetic dendrogram of partial C-prM gene of dengue virus type 2 (DENV-2) (a) and DENV-3 (b) causing the 2018 outbreak in Dhaka, Bangladesh (closed circle), and those from other diverse geographical locations, constructed by maximum likelihood method using the MEGA.7 software package. The tree was statistically supported by bootstrapping with 1000 replicates, and genetic distances were calculated using the Kimura two-parameter model. The variation scale is described at the bottom. Percentage bootstrap support is indicated by the values at each node (values <80 are omitted). Black square indicates a DENV-2 strain that was imported from Bangladesh to China (a) and DENV-3 strains detected in Bangladesh in 2002 (b). Genotypes of DENV-2 and DENV-3 are shown at right.
See this image and copyright information in PMC

References

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