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Case Reports
. 2019 Dec 26:27:39-41.
doi: 10.1016/j.mmcr.2019.12.003. eCollection 2020 Mar.

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Clarissa Mitri Espanhol  1 , Júlia Kanaan Recuero  1 , Danielle Machado Pagani  2 , Amanda Carvalho Ribeiro  3 , Gerson Vettorato  1 , Rodrigo Pereira Duquia  1 , Laura Luzzatto  4 , Maria Lúcia Scroferneker  4
Affiliations
Case Reports

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Clarissa Mitri Espanhol et al. Med Mycol Case Rep. .

Abstract

We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients.

Keywords: Exophiala xenobiotica; Immunosuppressed; Phaeohyphomycosis; Renal transplantation.

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Figures

Fig. 1
Fig. 1
(A) Fibrotic nodule in the right leg. (B) Fibrotic nodule - photo taken with dermlite 3gen DL4.
Fig. 2
Fig. 2
(A) Hematoxylin Eosin Stain. Leveduriform cells and brownish hyphae within a dermal infiltrate (400X magnification). (B) Direct mycological examination - dematiaceous septated hyphae (400X magnification).
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