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. 2020 Jan 7;15(1):e0227515.
doi: 10.1371/journal.pone.0227515. eCollection 2020.

Availability, prices and affordability of selected antibiotics and medicines against non-communicable diseases in western Cameroon and northeast DR Congo

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Availability, prices and affordability of selected antibiotics and medicines against non-communicable diseases in western Cameroon and northeast DR Congo

Simon Schäfermann et al. PLoS One. .

Abstract

Access to safe, effective and affordable medicines of good quality is included into the Sustainable Development Goals of the United Nations. Furthermore, WHO has developed a Global Action Plan with the aim to raise access to essential medicines against non-communicable diseases (NCDs) to 80%, and to improve their affordability. In order to contribute to the monitoring of progress towards these goals, the present study investigated the availability and affordability of seven antibiotics and six medicines against non-communicable diseases in the northeast of the Democratic Republic of Congo and the west of the Republic of Cameroon. Data on availability and prices of these medicines were collected in 60 different sites (34 in the DR Congo, 26 in Cameroon), including government health facilities, church health facilities, private pharmacies and informal vendors, as part of a study on medicine quality. The data were analyzed using a standardized procedure developed by WHO and Health Action International (HAI). Average availability of the investigated antibiotics ranged from 62% to 98% in the different types of facilities in both countries, including the informal vendors. Average availability for medicines against NCDs in the different types of facilities showed a higher variation in both countries, ranging from 11% up to 87%. The average availability of medicines against NCDs in government health facilities was only 33% in Cameroon, and as low as 11% in the DR Congo. In contrast, availability of medicines against NCDs in church health facilities in Cameroon was 70%, not far from the 80% availability goal set by WHO. Medicine prices were clearly higher in Cameroon than in the DR Congo, with median price ratios to an international reference price of 5.69 and 2.17, respectively (p < 0.001). In relation to the daily minimum wages in both countries, treatment courses with five of the seven investigated antibiotics could be considered as affordable, while in each country only one out of the five investigated medicines against NCDs could be considered as affordable. Especially generic medicines provided by government and church health facilities showed reasonable affordability in most cases, while originator medicines offered by private pharmacies were clearly unaffordable to a major part of the population. Despite some encouraging findings on the availability of antibiotics in both countries, the availability and affordability of medicines against NCDs urgently requires further improvements.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Map of the sampling regions, with numbers of medicines available at different types of facilities.
12 medicines were included into this study in each country. Therefore the maximum number of medicines recorded as available is 12. In the Ituri province in the DR Congo the health facilities under governmental authority were actually run by church organisations, therefore they were classified as church health facilities. * no informal vendor was identified in these health zones.
Fig 2
Fig 2. Availability of antibiotics and of medicines against non-communicable diseases in the four different types of health facilities.
Fig 3
Fig 3. Boxplots of the price ratios in the four different types of facilities.
Fig 4
Fig 4. Boxplots of the price ratios of the collected medicines sorted by API and country.
Fig 5
Fig 5. Median prices per treatment and median days’ wages needed for treatment.

References

    1. WHO Regional Office for South-East Asia: Health situation and trend assessment, MDG 8 essential medicines. http://www.searo.who.int/entity/health_situation_trends/data/mdg/drugs/en/.
    1. UN-DESA. Sustainable Development Goal 3, Progress of goal 3 in 2017. https://sustainabledevelopment.un.org/sdg3.
    1. WHO: Addressing the global shortage of, and access to, medicines and vaccines. Geneva, Switzerland. 2018. Executive Board 142nd session. Provisional agenda item EB142/13. http://apps.who.int/gb/ebwha/pdf_files/EB142/B142_13-en.pdf.
    1. WHO: Global Health Observation data repository, Median availability of selected generic medicines 2007–2013. Geneva, 2015. http://apps.who.int/gho/data/node.main.488?lang=en.
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