Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Apr;125(4):586-594.
doi: 10.1111/bju.14991. Epub 2020 Jan 24.

Evaluation of the economic burden of kidney stone disease in the UK: a retrospective cohort study with a mean follow-up of 19 years

Affiliations

Evaluation of the economic burden of kidney stone disease in the UK: a retrospective cohort study with a mean follow-up of 19 years

Robert M Geraghty et al. BJU Int. 2020 Apr.

Abstract

Objective: To estimate the cost of kidney stone disease (KSD) in England.

Patients and methods: We conducted a retrospective cohort study of patients with KSD, referred to a metabolic stone clinic between 1990 and 2007 using electronic records of patients with KSD in a tertiary referral centre, to determine cost using UK National Health Service (NHS) tariff, with subsequent extrapolation to the entire England population. Those with no documentation and <5 years follow-up were excluded. The outcome measure was calculation of cost (as per 2018 NHS tariff) presented as lower and higher estimates for: per episode; total within the cohort; and estimation of initial, 5-,10- and 15-year costs for the cohort and total population in England. Linear regression was used to examine for significant predictors of per episode and total cost.

Results: A total of 781 patients were included in the study after 1000 records were screened for inclusion, with a mean follow-up of 19 years. The mean (SD) overall costs per episode were between £1277 (1724) and £2887 (2492). Total initial costs for the cohort were between £950 842 and £2 336 442, rising to between £1.43 million and £3.02 million at 15 years of follow-up. Estimated cost in 2010 in England alone was between £190 million and £324 million.

Conclusion: KSD is a costly disease, comparable to the combined cost of prostate and bladder cancer in UK.

Keywords: cost; follow-up; kidney stone; obesity; treatment; urolithiasis.

PubMed Disclaimer

References

    1. Scales CD Jr, Smith AC, Hanley JM, Saigal CS, Urologic Diseases in America Project. Prevalence of kidney stones in the United States. Eur Urol 2012; 62: 160-5
    1. Penniston KL, Nakada SY. Urolithiasis/endourology development of an instrument to assess the health related quality of life of kidney stone formers. J Urol 2013; 189: 921-30
    1. Penniston KL, Antonelli JA, Viprakasit DP et al. Validation and reliability of the Wisconsin Stone Quality of Life Questionnaire. J Urol 2017; 197: 1280-8
    1. Lien CS, Huang CP, Chung CJ, Lin CL, Chang CH. Increased risk of anxiety among patients with urolithiasis: a nationwide population-based cohort study. Int J Urol 2015; 22: 937-42
    1. Rule AD, Bergstralh EJ, Melton LJ, Li X, Weaver AL, Lieske JC. Kidney stones and the risk for chronic kidney disease. Clin J Am Soc Nephrol 2009; 4: 804-11

Publication types