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Case Reports
. 2019 Nov;5(3):E89-E92.
doi: 10.1055/a-1061-7790. Epub 2020 Jan 8.

A Case of Unresectable Pancreatic Cancer with Long-Term Survival in High-Intensity Focused Ultrasound (HIFU) Therapy

Atsushi Sofuni  1 , Mitsuru Fujita  1 , Yasutsugu Asai  1 , Takayoshi Tsuchiya  1 , Kentaro Ishii  1 , Reina Tanaka  1 , Ryosuke Tonozuka  1 , Mitsuyoshi Honjo  1 , Shuntaro Mukai  1 , Kazumasa Nagai  1 , Kenjiro Yamamoto  1 , Yukitoshi Matsunami  1 , Takashi Kurosawa  1 , Hiroyuki Kojima  1 , Takao Itoi  1
Affiliations
Case Reports

A Case of Unresectable Pancreatic Cancer with Long-Term Survival in High-Intensity Focused Ultrasound (HIFU) Therapy

Atsushi Sofuni et al. Ultrasound Int Open. 2019 Nov.
No abstract available

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Conflict of interest statement

Conflict of Interest The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
CT imaging: a : CT before HIFU therapy showed a low-density mass (65 mm) infiltrating the CA and SMA in the pancreas body. b : CT imaging 3 months after HIFU therapy showed that the pancreas tumor had shrunk slightly. c : CT imaging after the second HIFU therapy (5 months after the first HIFU therapy) showed that the tumor had shrunk and PR in the therapeutic effect was obtained. d : CT imaging after the 4th HIFU therapy (19 months after the first HIFU therapy) showed the tumor size was unchanged (PR continued). e : CT imaging after the 7th HIFU therapy (39 months after the first HIFU therapy) showed continued PR until the patient passed away.
Fig. 2
Fig. 2
US imaging: a : B-mode US before HIFU therapy showed a hypoechoic mass (65 mm) in the pancreas body. b : CE-US before HIFU therapy showed an isovascular mass in the pancreas body. c : B-mode US after HIFU therapy showed echogenic change in the tumor post-HIFU therapy. d : CE-US after HIFU therapy showed a change in vascularity from isovascularity to hypovascularity
Fig. 3
Fig. 3
FEP-BY Series HIFU Therapy System: The system includes computer control, GE ultrasound imaging system, and treatment table with dual transducers.
Fig. 4
Fig. 4
Clinical course; each treatment, tumor size, tumor marker (CEA label), anti-tumor effect, pain relief control were showed in the monthly time series as the clinical course.
See this image and copyright information in PMC

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References

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