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Review
. 2020 Feb;20(2):75-76.
doi: 10.1038/s41577-020-0275-8.

Dissecting the mechanisms of immune checkpoint therapy

Padmanee Sharma  1   2 , James P Allison  3
Affiliations
Review

Dissecting the mechanisms of immune checkpoint therapy

Padmanee Sharma et al. Nat Rev Immunol. 2020 Feb.
No abstract available

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References

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    1. Fan, X. et al. Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy. J. Exp. Med. 211, 715–725 (2014). - DOI
    1. Wei, S. C. et al. Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies. Proc. Natl Acad. Sci. USA 116, 22699–22709 (2019). - DOI
    1. Kurtulus, S. et al. Checkpoint blockade immunotherapy induces dynamic changes in PD-1-CD8+ tumor-infiltrating T cells. Immunity 50, 181–194 (2019). - DOI

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