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. 2020 Mar;75(1):30-32.
doi: 10.1007/s11130-019-00791-1.

Honey as the Potential Natural Source of Cholinesterase Inhibitors in Alzheimer's Disease

Ewa Baranowska-Wójcik  1 , Dominik Szwajgier  2 , Anna Winiarska-Mieczan  3
Affiliations

Honey as the Potential Natural Source of Cholinesterase Inhibitors in Alzheimer's Disease

Ewa Baranowska-Wójcik et al. Plant Foods Hum Nutr. 2020 Mar.

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized, among others by abnormal levels of acetyl- and butyrylcholinesterase in the brain. In this study, 47 types of Polish honeys were examined (using colorimetric method) as a source of acetyl- and butyrylcholinesterase inhibitors. The highest potential for AChE inhibition was observed in the case of buckwheat honey (39.51% inhibition), while multi-floral honey showed the highest capacity for BChE inhibition (39.76%). Our study revealed that honeys can be a rich source of cholinesterase inhibitors and therefore may play a role in AD treatment.

Keywords: AChE; Acetylcholine; Alzheimer’s disease; BChE; Honey.

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References

    1. Curr Neuropharmacol. 2013 Jul;11(4):388-413 - PubMed
    1. Int J Alzheimers Dis. 2015;2015:903603 - PubMed
    1. Mini Rev Med Chem. 2016;16(8):605-18 - PubMed
    1. Med Sci (Basel). 2015 Apr 09;3(2):3-15 - PubMed

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