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Case Reports
. 2020 Oct-Dec;42(4):384-386.
doi: 10.1016/j.htct.2019.10.006. Epub 2019 Dec 18.

Blastic plasmacytoid dendritic cell neoplasm. A rare hematodermic malignancy

Deepa Goel  1 , Rahul Bhargava  2
Affiliations
Case Reports

Blastic plasmacytoid dendritic cell neoplasm. A rare hematodermic malignancy

Deepa Goel et al. Hematol Transfus Cell Ther. 2020 Oct-Dec.
No abstract available

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Figures

Figure 1
Figure 1
(a) A purplish nodule in right shoulder region. (b) PET-CT image with multiple FDG-avid subcutaneous nodules and enlarged lymph nodes. (c) The cells have a scant amount of cytoplasm with round-to-cleaved nuclei. Mitosis was frequent (H&E 40×). (d) Diffuse and strong cytoplasmic positivity for CD4 (40×). (e) Diffuse and strong positivity for CD56 (40×). (f) Moderate nuclear positivity in tumor cells for TdT (40×).
See this image and copyright information in PMC

References

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    1. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al., (Eds.), WHO classification of Tumors of Haematopoeitic and Lymphoid tissues, Revised 4th edition, 2017, IARC; Lyon.
    1. Petrella T., Comeau M.R., Maynadié M., Couillault G., De Muret A., Maliszewski C.R. Agranular CD4+CD56+ hematodermic neoplasm (blastic NK cell lymphoma) originates from a population of CD56+ precursor cells related to plasmacytoid monocytes. Am J Surg Pathol. 2002;26:852–862. - PubMed
    1. Adachi M., Maeda K., Takekawa M., Hinoda Y., Imai K., Sugiyama S. High expression of CD56 (N-CAM) in a patient with CD4-positive lymphoma. Am J Hematol. 1994;47:278–282. - PubMed
    1. Lee S.E., Park H.Y., Kwon D., Jeon Y.K., Kim W.Y. Blastic plasmacytoid dendritic cell neoplasm with unusual extracutaneous manifestation: two case reports and literature review. Medicine (Baltimore) 2019;98(6) - PMC - PubMed

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