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Case Reports
. 2019 Dec 9:2019:5130106.
doi: 10.1155/2019/5130106. eCollection 2019.

Riedel's Thyroiditis: Report of Two Cases and Literature Review

Victor Manuel Blanco  1 , Camilo Andrés Páez  1 , Angela María Victoria  2 , Luis Guillermo Arango  3 , Ana María Arrunategui  4 , Juliana Escobar  4 , Veline Martínez  1 , Guillermo Edinson Guzmán  3
Affiliations
Case Reports

Riedel's Thyroiditis: Report of Two Cases and Literature Review

Victor Manuel Blanco et al. Case Rep Endocrinol. .

Abstract

Riedel's thyroiditis is a rare entity consisting of a fibrotic process of the thyroid which can generate gland destruction, infiltration of cervical structures and even airway obstruction. It has been associated with systemic fibrotic disorders, autoimmune diseases, and more recently with spectrum of diseases related to excess of Immunoglobulin G type 4 (IgG4). Two cases of Riedel's thyroiditis by IgG4, confirmed by immunohistochemistry and was managed surgically with favorable results during the follow-up time, are presented. These case descriptions highlight the diagnostic challenge of this disease, describe the response with surgical management, and make a brief update on the subject.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Thyroid gland pathology. Hematoxylin and eosin stain of histological sample from case 1, showing fibrosis and tissue distortion. Original magnification ×20.
Figure 2
Figure 2
Thyroid gland pathology. Staining for IgG4. Multiple IgG4-positive cells were observed (brown color). Original magnification ×40.
Figure 3
Figure 3
Thyroid gland pathology. Hematoxylin and eosin stain of histological sample from case 2, showing fibrosis and tissue distortion. Original magnification ×20.
See this image and copyright information in PMC

References

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