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. 2020 Feb;35(2):370-371.
doi: 10.1002/mds.27979. Epub 2020 Jan 13.

Safety and efficacy of interferon γ in friedreich's ataxia

Marinela Vavla  1 , Maria Grazia D'Angelo  1 , Filippo Arrigoni  1 , Nicola Toschi  2   3 , Denis Peruzzo  1 , Sandra Gandossini  1 , Annamaria Russo  1 , Eleonora Diella  1 , Stefania Tirelli  1 , Roberto Salati  1 , Paolo Scarpazza  1 , Riccardo Luffarelli  2   4 , Silvia Fortuni  2 , Alessandra Rufini  2   4 , Ivano Condò  2 , Roberto Testi  2   4 , Andrea Martinuzzi  1
Affiliations

Safety and efficacy of interferon γ in friedreich's ataxia

Marinela Vavla et al. Mov Disord. 2020 Feb.
No abstract available

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References

    1. Koeppen AH, Mazurkiewicz JE. Friedreich ataxia: neuropathology revised. J Neuropathol Exp Neurol 2013;72(2):78-90.
    1. Tai G, Corben LA, Yiu EM, Milne SC, Delatycki MB. Progress in the treatment of Friedreich ataxia. Neurol Neurochir Pol 2018;52(2):129-139.
    1. Tomassini B, Arcuri G, Fortuni S, et al. Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model. Hum Mol Genet 2012;21(13):2855-2861.
    1. Seyer L, Greeley N, Foerster D, et al. Open-label pilot study of interferon gamma-1b in Friedreich ataxia. Acta Neurol Scand 2015;132(1):7-15.
    1. Marcotulli C, Fortuni S, Arcuri G, et al. GIFT-1, a phase IIa clinical trial to test the safety and efficacy of IFNgamma administration in FRDA patients. Neurol Sci 2016;37(3):361-364.

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