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. 2020 Jun:138:645-653.
doi: 10.1016/j.wneu.2020.01.014. Epub 2020 Jan 10.

The Value of Obstetric Ultrasound in Screening Fetal Nervous System Malformation

Na Zhang  1 , Han Dong  2 , Ping Wang  1 , Zhihui Wang  1 , Yuchong Wang  3 , Zhiheng Guo  4
Affiliations

The Value of Obstetric Ultrasound in Screening Fetal Nervous System Malformation

Na Zhang et al. World Neurosurg. 2020 Jun.

Abstract

Background: The article uses ultrasound imaging standard section to examine the fetal central nervous system (CNS) in early pregnancy, combined with ultrasound imaging in the diagnosis of fetal CNS malformation in the middle and late pregnancy, to determine the feasibility of ultrasound imaging in the detection of CNS abnormalities in the first trimester of the fetus.

Methods: The article selected 2701 pregnant women from the Department of Ultrasound in our hospital from November 2012 to November 2016 to screen for the transparent layer of the fetal neck in early pregnancy, with a total of 2751 cases. The article uses Madison V20 and Madison XG color Doppler ultrasound diagnostic instruments, the probe frequency is measured from 2.0-3.5 MHz, grouped according to gestational age, the statistical section of the case is displayed, and the transparent layer of the neck value is used to count the ultrasound image during early pregnancy. The detection of the CNS malformation by the standard section examination and the sensitivity, specificity, positive predictive value, and negative predictive value of the diagnosis may affect the cause of the CNS display rate.

Results: The sensitivity, specificity, positive predictive value, and negative predictive value of the ultrasound standard section in the diagnosis of fetal CNS malformation in early pregnancy were 85.7%, 100%, 100%, and 99.9%, respectively. Through research, it is found that the use of ultrasound imaging standard section can effectively diagnose fetal CNS severe deformity in early pregnancy, and the detection rate of CNS malformation in early pregnancy is 85.7%. At the same time, the number of positive cases and CNS malformations in this group were few.

Conclusions: The positive cases detected in early pregnancy were severe malformations of the CNS. The diagnosis of other CNS malformations in the fetus needs further study.

Keywords: Fetal nervous system; NT examination; Prenatal ultrasound diagnosis.

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