Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Feb:49:267-273.
doi: 10.1016/j.breast.2019.12.007. Epub 2019 Dec 19.

Artificial intelligence in digital breast pathology: Techniques and applications

Affiliations
Review

Artificial intelligence in digital breast pathology: Techniques and applications

Asmaa Ibrahim et al. Breast. 2020 Feb.

Abstract

Breast cancer is the most common cancer and second leading cause of cancer-related death worldwide. The mainstay of breast cancer workup is histopathological diagnosis - which guides therapy and prognosis. However, emerging knowledge about the complex nature of cancer and the availability of tailored therapies have exposed opportunities for improvements in diagnostic precision. In parallel, advances in artificial intelligence (AI) along with the growing digitization of pathology slides for the primary diagnosis are a promising approach to meet the demand for more accurate detection, classification and prediction of behaviour of breast tumours. In this article, we cover the current and prospective uses of AI in digital pathology for breast cancer, review the basics of digital pathology and AI, and outline outstanding challenges in the field.

Keywords: (Artificial intelligence); (Deep learning); (Machine learning); (Whole slide image); AI; Applications; Breast cancer; Breast pathology; DL; Digital; ML; Pathology; WSI.

PubMed Disclaimer

References

    1. Gomes D.S., Porto S.S., Balabram D., Gobbi H. Inter-observer variability between general pathologists and a specialist in breast pathology in the diagnosis of lobular neoplasia, columnar cell lesions, atypical ductal hyperplasia and ductal carcinoma in situ of the breast. Diagn Pathol. 2014;9:121. - PMC - PubMed
    1. Allison K.H., Reisch L.M., Carney P.A. Understanding diagnostic variability in breast pathology: lessons learned from an expert consensus review panel. Histopathology. 2014;65(2):240–251. - PMC - PubMed
    1. Robertson S., Azizpour H., Smith K., Hartman J. Digital image analysis in breast pathology-from image processing techniques to artificial intelligence. Transl Res. 2018;194:19–35. - PubMed
    1. Gulshan V., Peng L., Coram M. Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. J Am Med Assoc. 2016;316(22):2402–2410. - PubMed
    1. Liu Y., Chen P.-H.C., Krause J., Peng L. How to read articles that use machine learning: users’ guides to the medical literature. J Am Med Assoc. 2019;322(18):1806–1816. - PubMed

MeSH terms