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Review
. 2020 Jan 8;8(1):85.
doi: 10.3390/microorganisms8010085.

The Use of Antimalarial Drugs against Viral Infection

Sarah D'Alessandro  1 , Diletta Scaccabarozzi  2 , Lucia Signorini  1 , Federica Perego  1 , Denise P Ilboudo  3 , Pasquale Ferrante  1 , Serena Delbue  1
Affiliations
Review

The Use of Antimalarial Drugs against Viral Infection

Sarah D'Alessandro et al. Microorganisms. .

Abstract

In recent decades, drugs used to treat malaria infection have been shown to be beneficial for many other diseases, including viral infections. In particular, they have received special attention due to the lack of effective antiviral drugs against new emerging viruses (i.e., HIV, dengue virus, chikungunya virus, Ebola virus, etc.) or against classic infections due to drug-resistant viral strains (i.e., human cytomegalovirus). Here, we reviewed the in vitro/in vivo and clinical studies conducted to evaluate the antiviral activities of four classes of antimalarial drugs: Artemisinin derivatives, aryl-aminoalcohols, aminoquinolines, and antimicrobial drugs.

Keywords: antimalarial drugs; emerging infections; viruses.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chemical structures of the compounds described in the text.
See this image and copyright information in PMC

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