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. 2020 Jan 9;12(1):187.
doi: 10.3390/nu12010187.

Short-Term Effect of One-Anastomosis Gastric Bypass on Essential Fatty Acids in the Serum of Obese Patients

Adriana Mika  1   2 , Maciej Wilczynski  3 , Alicja Pakiet  2 , Lukasz Kaska  3 , Monika Proczko-Stepaniak  3 , Marta Stankiewicz  4 , Piotr Stepnowski  2 , Tomasz Sledzinski  1
Affiliations

Short-Term Effect of One-Anastomosis Gastric Bypass on Essential Fatty Acids in the Serum of Obese Patients

Adriana Mika et al. Nutrients. .

Abstract

One-anastomosis gastric bypass is a promising type of bariatric surgery, but it may lead to a deficiency in important nutrients, such as fatty acids. The short-term effects of one-anastomosis gastric bypass on serum fatty acids have not been studied thus far. Therefore, the aim of this study was to determine the effect of one-anastomosis gastric bypass on serum fatty acid composition two weeks after surgery. This study included 38 patients who underwent one-anastomosis gastric bypass as surgical treatment for morbid obesity. Serum fatty acid composition was analyzed before and two weeks after surgery using gas chromatography-mass spectrometry. We observed a decrease in essential polyunsaturated fatty acids (p < 0.001 for linolenic acid and p < 0.001 for linoleic acid) and odd-chain fatty acids (p = 0.004) in the serum of obese patients shortly after a one-anastomosis gastric bypass. Considering the benefits of the aforementioned fatty acids for human health, the implementation of a fatty-acid-rich diet or the use of supplementation may be recommended for patients immediately after one-anastomosis gastric bypass.

Keywords: essential fatty acids; obesity; odd-chain fatty acids; one-anastomosis gastric bypass.

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Conflict of interest statement

The authors declare no conflict of interest. The benefactors had no role in the design of the study, the collection, analyses, or interpretation of data, the writing of the manuscript, or the decision to publish the results.

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