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Case Reports
. 2018 Apr 1;11(4):2142-2147.
eCollection 2018.

Yolk sac tumor of ear: a case report and literature review of the last 30 years

Hongmiao Ren  1 , Huiwen Zhuang  1 , Guanxia Xiong  1
Affiliations
Case Reports

Yolk sac tumor of ear: a case report and literature review of the last 30 years

Hongmiao Ren et al. Int J Clin Exp Pathol. .

Abstract

Extra-gonadal pure yolk sac tumor of the ear is very rare. We report a case of a yolk sac tumor of the ear and review the English literature in PubMed. The initial complaint was a mass protruding out of the external auditory canal. Computed tomography (CT) showed a large irregularly enhancing isodense mass lesion measuring 42*16 mm in the right external auditory canal, the right mastoid process, and extending to the right back parapharyngeal space with unclear border. Laboratory studies revealed that serum alpha fetoprotein (AFP) was significantly elevated at 664.60 ng/ml (range, 0 to 25 ng/ml), and neuron-specific enolase (NSE) was 28.3 ng/ml (range, 0 to 16.3 ng/ml). After finishing 6 cycles of chemotherapy, the patient underwent a total resection of yolk sac tumor of the ear. In addition, we review the English literature of the yolk sac tumor of the ear.

Keywords: Yolk sac tumor; ear; external auditory canal.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
(A, B) The tumor located underneath the epidermis with partially ulceration. The loose meshwork of interconnected spaces and small cysts were lined by round or ovary tumor cells with the primitive appearance. The papillary fibrovascular core lined by a single layer of tumor cells. (C) Pathognomonic Schiller-Duval bodies were poorly formed. Hyaline globules could be found in the stroma. (The magnification of the (A-C) are 100, 200, and 200, respectively).
Figure 2
Figure 2
The tumor before chemotherapy measured 87*66 mm.
Figure 3
Figure 3
Temporal bone computed tomography scan showed a large irregularly enhancing isodense mass lesion measuring 87*66 mm in the right external auditory canal, the right mastoid process, and extending to the right back parapharyngeal space with unclear border. (Illustration: Diao Zehong, 14 months, M.0877639; Head examination; Sep/05/2015; Patient’s position: HFS; Exammination #: 201511050252; Series: 7.5 mm Stnd (A-C), 7.5 mm Stnd (D-F); GE MEDICAL SYSTEMS Optima; 100 KV, 9 mAs (A), 55 mAs (B-F), Sweep range: 320.00 mm; 100% pixel; Orginal resolution).
Figure 4
Figure 4
Temporal bone computed tomography scan showed no mass in both the right middle ear and external auditory canal.
See this image and copyright information in PMC

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