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. 2020 Jan 10:18:eAO4433.
doi: 10.31744/einstein_journal/2020AO4433. eCollection 2020.

Pharmaceutical intervention in the rational use of intravenous omeprazole

[Article in English, Portuguese]
Eduardo Silva Araújo  1 , Ana Carolina Figueiredo Modesto  2 , Tatyana Xavier Almeida Matteucci Ferreira  2 , Mércia Pandolfo Provin  3 , Dione Marçal Lima  3 , Rita Goreti Amaral  3
Affiliations

Pharmaceutical intervention in the rational use of intravenous omeprazole

[Article in English, Portuguese]
Eduardo Silva Araújo et al. Einstein (Sao Paulo). .

Abstract
in English, Portuguese

Objective: To describe the pharmaceutical interventions of a vertical clinical pharmacy service to promote the rational use of intravenous omeprazole.

Methods: A prospective and descriptive study carried out at a university hospital in the Midwestern Region of Brazil, from November 2014 to May 2015. The service consisted of the analysis of adequacy of the route of administration of omeprazole in relation to the clinical conditions of the patient, as well as the use of the appropriate diluent. Interventions were recorded in medical records and subsequently evaluated for acceptance.

Results: A total of 770 prescriptions were evaluated. Interventions related to diluent replacement were more accepted (p<0.001), and surgeons were the specialty that used the intravenous route inappropriately (p<0.001).

Conclusion: Although partially accepted, pharmaceutical interventions could contribute to improve patient safety, since they allowed the use of a safer route of administration.

Objetivo:: Descrever as intervenções farmacêuticas de um serviço farmacêutico clínico vertical, para a promoção do uso racional do omeprazol intravenoso.

Métodos:: Estudo prospectivo e descritivo realizado em um hospital universitário da região Centro-Oeste do Brasil, no período de novembro de 2014 a maio de 2015. O serviço consistia na análise da adequabilidade da via de administração do omeprazol em relação às condições clínicas do paciente, bem como a utilização do diluente adequado. As intervenções eram registradas em prontuário e, posteriormente, avaliadas quanto à aceitação.

Resultados:: Foram avaliadas 770 prescrições. As intervenções relacionadas à substituição do diluente foram mais aceitas (p<0,001), e os cirurgiões foram a especialidade que utilizou a via intravenosa de maneira inadequada (p<0,001).

Conclusão:: Embora parcialmente aceitas, as intervenções farmacêuticas puderam contribuir com a melhoria da segurança dos pacientes, uma vez que permitiram a utilização de uma via de administração mais segura.

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Conflict of interest statement

Conflict of interest: none.

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