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Review
. 2020 Apr;39(4):529-533.
doi: 10.1097/ICO.0000000000002246.

Current Global Bioethical Dilemmas in Corneal Transplantation

Affiliations
Review

Current Global Bioethical Dilemmas in Corneal Transplantation

Andrea Córdoba et al. Cornea. 2020 Apr.

Abstract

Purpose: To analyze some of the bioethical dilemmas that may arise during the process required for corneal transplantation.

Methods: We conducted a narrative review based on the available literature and the experience of cornea specialists from 3 different countries.

Results: Bioethical dilemmas related to informed consent for organ and tissue donation, allocation of corneal tissues, transplant tourism, corneal tissue exportation and importation, and for-profit eye banking were analyzed and discussed.

Conclusions: Around the world, the number of required corneal transplants exceeds the number of donated corneas that are available and suitable for transplantation. This shortage of corneal tissue has led to the emergence of practices that may put the 4 basic principles of bioethics at risk: autonomy, beneficence, nonmaleficence, and justice. Therefore, it has been necessary to create ethical guidelines such as the Barcelona Principles and the World Health Organization Principles of Transplantation that attempt to regulate these practices.

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References

    1. Srur L, Martén L, Wang MX, et al. Corneal surgery. In: Yanoff M, Duker JS. eds. Ophthalmology. 4th ed. Philadelphia, PA: Mosby Elsevier; 2014:299–307.
    1. Gain P, Jullienne R, He Z, et al. Global survey of corneal transplantation and eye banking. JAMA Ophthalmol. 2016;134:167–173.
    1. Martin DE, Van Assche K, Domínguez-Gil B, et al. Strengthening global efforts to combat organ trafficking and transplant tourism: implications of the 2018 edition of the declaration of Istanbul. Transplant Direct. 2019;5:e433.
    1. Beauchamp TL, Childress JF. Principles of Biomedical Ethics. 7th ed. Oxford, England: Oxford University Press; 2013.
    1. World Health Organization (WHA63.22). Guiding principles on human cell, tissue and organ transplantation. 2010. Available at: www.who.int/entity/transplantation/Guiding_PrinciplesTransplantation_WHA.... Accessed January 17, 2019.

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