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. 2019 Dec 25;12(4):507-513.
doi: 10.3400/avd.oa.19-00033.

Characteristics and Surgical Results of Acute Type A Aortic Dissection in Patients Younger Than 50 Years of Age

Kentaro Tamura  1 , Genta Chikazawa  1 , Arudo Hiraoka  1 , Toshinori Totsugawa  1 , Hidenori Yoshitaka  1
Affiliations

Characteristics and Surgical Results of Acute Type A Aortic Dissection in Patients Younger Than 50 Years of Age

Kentaro Tamura et al. Ann Vasc Dis. .

Abstract

Objectives: The aim of this study is to investigate the characteristics and surgical outcomes of acute type A aortic dissection (AAAD) in patients younger than 50 years of age. Methods: We retrospectively evaluated 307 patients who consecutively underwent surgical treatment for AAAD in our institute from January 2007 to June 2017. Patients were classified into two groups: the young group with 31 patients aged younger than 50 and the old group with 276 patients aged 50 years or older. Results: In-hospital mortality was similar in both groups (3.2% vs. 9.4%, p=0.19). Overall survival at 5 years was higher in the young group than that in the old group (97% vs. 71%, p=0.017). No significant differences were observed in freedom from aorta-related death and distal aortic reoperation at 5 years (97% vs. 87%, p=0.26; 86% vs. 92%, p=0.093). The percentage of young patients with postoperative patent false lumen at the descending aorta was significantly higher than that of old patients (76% vs. 30%, p<0.001) in spite of primary entry resection. Conclusion: Early and mid-term outcomes for AAAD in young patients were satisfactory. However, future follow-up is important because postoperative patent false lumen is at a high rate in young patients in spite of entry resection.

Keywords: aortic dissection.

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Conflict of interest statement

Disclosure StatementThe authors have nothing to disclose with regard to commercial support.

Figures

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Fig. 1 Kaplan–Meier curves of the overall survival rate in the young and old groups.
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Fig. 2 Kaplan–Meier curves of freedom from aorta-related death in the young and old groups.
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Fig. 3 Kaplan–Meier curves of freedom from distal aortic reoperation.
See this image and copyright information in PMC

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