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Review
. 2019 May 31;2(2):88-93.
doi: 10.1002/agm2.12069. eCollection 2019 Jun.

Advances in screening instruments for Alzheimer's disease

Xianbo Zhou  1   2 , J Wesson Ashford  3   4
Affiliations
Review

Advances in screening instruments for Alzheimer's disease

Xianbo Zhou et al. Aging Med (Milton). .

Abstract

At its fundamental basis, Alzheimer's disease (AD) is a pathological process that affects neuroplasticity, leading to a specific disruption of episodic memory. This review will provide a rationale for calls to screen for the early detection of AD, appraise the currently available cognitive instruments for AD detection, and focus on the development of the MemTrax test, which provides a new approach to detect the early manifestations and progression of the dementia associated with AD. MemTrax assesses metrics that reflect the effects of neuroplastic processes on learning, memory, and cognition, which are affected by age and AD, particularly episodic memory functions, which cannot presently be measured with enough precision for meaningful use. Further development of MemTrax would be of great value to the early detection of AD and would provide support for the testing of early interventions.

Keywords: Alzheimer's disease; screen; screening instrument.

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Conflict of interest statement

Xianbo Zhou: I serve as the General Manager and Legal Representative for SJN Biomed LTD, which brought the MemTrax memory test to China. J. Wesson Ashford: Patents/Royalties: I serve as an unpaid scientific advisor to MemTrax, LLC (a company managed by my adult son, Curtis Ashford).

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