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. 2020 Jan 16;77(2):210-212.
doi: 10.1016/j.molcel.2019.12.016.

Prime Editing: Precision Genome Editing by Reverse Transcription

Jun Yan  1 , Ann Cirincione  2 , Britt Adamson  3
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Prime Editing: Precision Genome Editing by Reverse Transcription

Jun Yan et al. Mol Cell. .
Free article

Abstract

Genome editing is a method for making targeted sequence changes to the genomes of living cells. Prime editing, recently reported by Anzalone et al. (2019), is a new technology that uses reverse transcription to "write" programmed sequence changes into genomic DNA and thus promises significant technical advances.

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