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. 2020 Jan 17;20(1):29.
doi: 10.1186/s12886-020-1313-9.

Povidone-iodine pharmacokinetics and study design

Jagger Koerner  1 , Andrzej Grzybowski  2
Affiliations

Povidone-iodine pharmacokinetics and study design

Jagger Koerner et al. BMC Ophthalmol. .

Abstract

Dr. Gnanasekaran et al. reported the bactericidal activity of various concentrations of povidone iodine (PI) solution in an agar plate experiment of respiratory flora. The study design and the pharmacokinetic properties of PI solution ensured that dilute PI would not be effective in this study. These results may not replicate the typical clinical situation and are significantly different than a previously reported agar plate experiment, again owing to subtle but very significant differences in methodology.

Keywords: Endophthalmitis prophylaxis; Intravitreal injection; Povidone-iodine.

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Conflict of interest statement

The authors declare that they have no competing interests.

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References

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