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Review
. 2020 Jan-Feb;95(1):82-90.
doi: 10.1016/j.abd.2019.09.025. Epub 2019 Dec 18.

Safety of local anesthetics

Ana Carolina Figueiredo Pereira Cherobin  1 , Glaysson Tassara Tavares  2
Affiliations
Review

Safety of local anesthetics

Ana Carolina Figueiredo Pereira Cherobin et al. An Bras Dermatol. 2020 Jan-Feb.

Abstract

Local anesthetics are essential medications for the conduction of dermatological procedures. They stop the depolarization of nerve fibers and are divided into two main categories, the amide and ester types. Systemic toxicity with reflex on the central nervous and cardiovascular systems is their most feared adverse reactions, and the anaphylactic reaction is the most concerning one. Although potentially fatal, these events are extremely rare, so local anesthetics are considered safe for use in in-office procedures.

Keywords: Anaphylaxis; Anesthetics, local; Drug-related side effects and adverse reactions.

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