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Comment
. 2020 Feb;43(2):75-77.
doi: 10.1016/j.tins.2019.12.005. Epub 2020 Jan 15.

Evolutionary Expansion of Human Cerebellar Germinal Zones

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Comment

Evolutionary Expansion of Human Cerebellar Germinal Zones

Matthew G Keefe et al. Trends Neurosci. 2020 Feb.

Abstract

Haldipur et al. explored the developmental origins of the human cerebellum, which has gained growing appreciation for its involvement in human cognition. The authors discovered human-unique expansion and maintenance of cerebellar germinal zones, reminiscent of processes in the developing human cerebral cortex necessary for generating expanded neuronal populations.

Keywords: brain evolution; cerebellar development; human neurogenesis.

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  • Spatiotemporal expansion of primary progenitor zones in the developing human cerebellum.
    Haldipur P, Aldinger KA, Bernardo S, Deng M, Timms AE, Overman LM, Winter C, Lisgo SN, Razavi F, Silvestri E, Manganaro L, Adle-Biassette H, Guimiot F, Russo R, Kidron D, Hof PR, Gerrelli D, Lindsay SJ, Dobyns WB, Glass IA, Alexandre P, Millen KJ. Haldipur P, et al. Science. 2019 Oct 25;366(6464):454-460. doi: 10.1126/science.aax7526. Epub 2019 Oct 17. Science. 2019. PMID: 31624095 Free PMC article.

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