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Review
. 2020 Feb;36(1):150983.
doi: 10.1016/j.soncn.2019.150983. Epub 2020 Jan 18.

Proactive Rehabilitation for Chemotherapy-Induced Peripheral Neuropathy

Robert Knoerl  1 , Laura Gilchrist  2 , Grace A Kanzawa-Lee  3 , Clare Donohoe  3 , Celia Bridges  3 , Ellen M Lavoie Smith  3
Affiliations
Review

Proactive Rehabilitation for Chemotherapy-Induced Peripheral Neuropathy

Robert Knoerl et al. Semin Oncol Nurs. 2020 Feb.

Abstract

Objective: To review assessment and management approaches for chemotherapy-induced peripheral neuropathy-related physical function deficits.

Data sources: Peer-reviewed articles from PubMed, Ovid MEDLINE, CINAHL PsycINFO, SPORTDiscus, Scopus, and key studies' reference lists.

Conclusion: Brief clinical tests (eg, gait, Timed Up and Go) can screen for neuropathy-related physical function deficits. Exercise and physical therapy may be promising treatments, but the efficacy and optimal dose of such treatments for chemotherapy-induced peripheral neuropathy are unclear.

Implications for nursing practice: Screening and assessment of neuropathy-associated physical function deficits should occur throughout neurotoxic chemotherapy treatment. If such deficits are identified, referral for rehabilitation (ie, physical or occupational therapy) and/or exercise interventions is warranted.

Keywords: Chemotherapy-induced peripheral Neuropathy; Exercise; Neuropathic pain; Physical therapy modalities; Rehabilitation.

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Conflict of interest statement

Conflict of Interest None.

References

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