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Case Reports
. 2020 Feb;26(2):362-364.
doi: 10.3201/eid2602.181667.

Rickettsia mongolitimonae Encephalitis, Southern France, 2018

María Dolores Corbacho Loarte, Cléa Melenotte, Nadim Cassir, Serge Cammilleri, Philippe Dory-Lautrec, Didier Raoult, Philippe Parola
Case Reports

Rickettsia mongolitimonae Encephalitis, Southern France, 2018

María Dolores Corbacho Loarte et al. Emerg Infect Dis. 2020 Feb.

Abstract

We report a case of Rickettsia sibirica mongolitimonae infection, an emerging tickborne rickettsiosis, with associated encephalitis in a 66-year-old man. Diagnosis was rapidly confirmed by quantitative PCR obtained from an eschar swab sample. The patient was successfully treated with oral doxycycline.

Keywords: France; Rickettsia mongolitimonae; bacteria; meningitis/encephalitis; tickborne rickettsioses; ticks; vector-borne infections.

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Figures

Figure
Figure
Clinical manifestations and cerebral magnetic resonance imaging of a 66-year-old man with Rickettsia sibirica mongolitimonae–associated encephalitis, southern France, 2018. A) Maculopapular rash. B) Black eschar and rope-like lymphangitis on the right leg. C) Magnetic resonance imaging with diffusion (B1000), ADC, and FLAIR. In July 2018, cytotoxic lesions were observed intra-axially and in the white matter of right cerebellar hemispheres with FLAIR hypersignal and with low ADC signal. In September 2018, these cytotoxic lesions regressed in diffusion with the appearance of a necrotic cavity facing the roof of the left lateral ventricle. In July 2019, disappearance of diffusion anomalies. Small necrotic cavity with after-effects on FLAIR and ADC signals. ADC, apparent diffusion coefficient; FLAIR, fluid-attenuated inversion recovery.
See this image and copyright information in PMC

References

    1. Rajoelison P, Mediannikov O, Javelle E, Raoult D, Parola P, Aoun O. Rickettsia sibirica mongolitimonae human infection: A diagnostic challenge. Travel Med Infect Dis. 2018;26:72–3. 10.1016/j.tmaid.2018.07.002 - DOI - PubMed
    1. Parola P, Paddock CD, Socolovschi C, Labruna MB, Mediannikov O, Kernif T, et al. Update on tick-borne rickettsioses around the world: a geographic approach. Clin Microbiol Rev. 2013;26:657–702. 10.1128/CMR.00032-13 - DOI - PMC - PubMed
    1. Solary J, Socolovschi C, Aubry C, Brouqui P, Raoult D, Parola P. Detection of Rickettsia sibirica mongolitimonae by using cutaneous swab samples and quantitative PCR. Emerg Infect Dis. 2014;20:716–8. 10.3201/eid2004.130575 - DOI - PMC - PubMed
    1. Kuscu F, Orkun O, Ulu A, Kurtaran B, Komur S, Inal AS, et al. Rickettsia sibirica mongolitimonae Infection, Turkey, 2016. Emerg Infect Dis. 2017;23:1214–6. 10.3201/eid2307.170188 - DOI - PMC - PubMed
    1. Nouchi A, Monsel G, Jaspard M, Jannic A, Angelakis E, Caumes E. Rickettsia sibirica mongolitimonae infection in a woman travelling from Cameroon: a case report and review of the literature. J Travel Med. 2018;25:25. 10.1093/jtm/tax074 - DOI - PubMed

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