Mutations in the hemagglutinin gene associated with influenza virus resistance to norakin
- PMID: 3196166
- DOI: 10.1007/BF01315569
Mutations in the hemagglutinin gene associated with influenza virus resistance to norakin
Abstract
The nucleotide sequences of the hemagglutinin genes of four norakin-resistant mutants of Influenza A/FPV/Weybridge were determined and compared to the wild-type hemagglutinin. All mutants show one or two amino acid substitutions which are discussed to destabilise the pH 7 conformation of hemagglutinin.
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