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. 1988 Oct 1;255(1):79-83.
doi: 10.1042/bj2550079.

The structure of the human glutathione S-transferase pi gene

I G Cowell  1 , K H Dixon, S E Pemble, B Ketterer, J B Taylor
Affiliations

The structure of the human glutathione S-transferase pi gene

I G Cowell et al. Biochem J. .

Abstract

The human glutathione S-transferase pi gene has been isolated from a cosmid library. The gene spans approximately 3 kb, is interrupted by six introns and the region around its 5' end has the high G + C and CpG content typical of an HTF (HpaII tiny fragment) island. In addition to a TATA box at position -28 relative to the transcription initiation site and two G + C boxes (GGGCGG), the promoter contains a sequence motif matching the phorbol ester- and ras-responsive element from the polyoma virus enhancer.

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References

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