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. 1988 Nov 30;157(1):389-94.
doi: 10.1016/s0006-291x(88)80059-7.

Synthetic ferrichrome analogues with growth promotion activity for Arthrobacter flavescens

A Shanzer  1 , J Libman, R Lazar, Y Tor, T Emery
Affiliations

Synthetic ferrichrome analogues with growth promotion activity for Arthrobacter flavescens

A Shanzer et al. Biochem Biophys Res Commun. .

Abstract

Two families of trihydroxamic acid analogues of ferrichrome were chemically synthesized and tested for biological activity with Arthrobacter flavescens. Compounds using a tertiary amine as anchor showed little activity. Several compounds using tetrahedral carbon as anchor showed activity approaching or equalling that of the natural siderophore, ferrichrome. The biological activity is discussed in relation to physical and chemical properties of the analogues.

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