Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Feb;26(2):307-310.
doi: 10.3201/eid2602.171636.

Emergence of Chikungunya Virus, Pakistan, 2016-2017

Nazish Badar, Muhammad Salman, Jamil Ansari, Uzma Aamir, Muhammad Masroor Alam, Yasir Arshad, Nighat Mushtaq, Aamer Ikram, Javaria Qazi

Emergence of Chikungunya Virus, Pakistan, 2016-2017

Nazish Badar et al. Emerg Infect Dis. 2020 Feb.

Abstract

During December 2016-May 2017, an outbreak of chikungunya virus infection occurred across Pakistan. The East/Central/South African genotype was predominant. This study provides baseline data on the virus strain and emphasizes the need for active surveillance and implementation of preventive interventions to contain future outbreaks.

Keywords: CHIKV; Chikungunya virus; Pakistan; arboviruses; molecular epidemiology; vector-borne infections; viruses; zoonoses.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Geographic distribution of chikungunya-positive cases in Pakistan, December 20, 2016–May 31, 2017. AJK, Azad Jammu and Kashmir; FATA, Federally Administered Tribal Areas.
Figure 2
Figure 2
Phylogenetic tree of chikungunya viruses collected from patients in Pakistan, December 20, 2016–May 31, 2017 (red squares), and reference viruses. The tree was generated by the maximum-likelihood method based on the nucleotide sequence of the partial envelope 1 (A) and nonstructural protein 1 (B) genes. Red text indicates East/Central/South African genotype; yellow text indicates Asian genotype; green text indicates South African genotype; blue text indicates West African genotype; and purple text indicates o’nyong-nyong virus ancestral strain. GenBank accession numbers are provided for reference viruses. Scale bars indicate nucleotide substitutions per site.
See this image and copyright information in PMC

References

    1. Weaver SC, Osorio JE, Livengood JA, Chen R, Stinchcomb DT. Chikungunya virus and prospects for a vaccine. Expert Rev Vaccines. 2012;11:1087–101. 10.1586/erv.12.84 - DOI - PMC - PubMed
    1. Burt FJ, Rolph MS, Rulli NE, Mahalingam S, Heise MT. Chikungunya: a re-emerging virus. Lancet. 2012;379:662–71. 10.1016/S0140-6736(11)60281-X - DOI - PubMed
    1. Thiberville S-D, Moyen N, Dupuis-Maguiraga L, Nougairede A, Gould EA, Roques P, et al. Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy. Antiviral Res. 2013;99:345–70. 10.1016/j.antiviral.2013.06.009 - DOI - PMC - PubMed
    1. Darwish MA, Hoogstraal H, Roberts TJ, Ahmed IP, Omar F. A sero-epidemiological survey for certain arboviruses (Togaviridae) in Pakistan. Trans R Soc Trop Med Hyg. 1983;77:442–5. 10.1016/0035-9203(83)90106-2 - DOI - PubMed
    1. Aamir UB, Badar N, Salman M, Ahmed M, Alam MM. Outbreaks of chikungunya in Pakistan. Lancet Infect Dis. 2017;17:483. 10.1016/S1473-3099(17)30191-3 - DOI - PubMed

Publication types

MeSH terms