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Review
. 2019 Dec 15:125 Suppl 24:4573-4577.
doi: 10.1002/cncr.32514.

How to manage lymph nodes in ovarian cancer

Philipp Harter  1 , Florian Heitz  1 , Beyhan Ataseven  1   2 , Stephanie Schneider  1 , Thais Baert  1   3 , Sonia Prader  1 , Andreas du Bois  1
Affiliations
Free article
Review

How to manage lymph nodes in ovarian cancer

Philipp Harter et al. Cancer. .
Free article

Abstract

The indication for staging lymphadenectomy in patients with ovarian cancer (both early- and late-stage disease) has been a major topic of debate in the last decades. Because the Lymphadenectomy in Ovarian Neoplasms (LION) study has recently demonstrated that systematic lymphadenectomy is not beneficial to patients with advanced ovarian cancer, the discussion has become more complex for patients with early-stage ovarian cancer. Further factors, such as differences in the lymph node metastasis rates of different histologic subtypes, which were not known in the past, need to be taken into account. This review is focused on the available evidence concerning lymphadenectomy in patients with newly diagnosed ovarian cancer.

Keywords: Lymphadenectomy in Ovarian Neoplasms (LION); advanced ovarian cancer; early ovarian cancer; lymphadenectomy.

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References

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