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Observational Study
. 2020 Jun;26(3):358-363.
doi: 10.1177/1591019919898923. Epub 2020 Jan 22.

Initial experience with React 68 aspiration catheter

Scott B Raymond  1 , Mehr Nasir-Moin  2 , Matthew J Koch  2 , James D Rabinov  2   3 , Thabele Leslie-Mazwi  2   4 , Aman B Patel  2
Affiliations
Observational Study

Initial experience with React 68 aspiration catheter

Scott B Raymond et al. Interv Neuroradiol. 2020 Jun.

Abstract

Introduction: We describe our initial experience with the React 68 catheter (Medtronic, Dublin, Ireland), an FDA-approved catheter designed for aspiration in cases of emergent large vessel occlusion, as compared with the ACE 68 catheter (Penumbra, Alameda, CA).

Methods: This observational study followed consecutive patients treated with the React catheter over a seven-month period at a comprehensive stroke center. Use of the device was per discretion of the operator. Patient demographics, thrombectomy technique, reperfusion scoring, and disposition were assessed. Performance was compared with patients treated with the ACE 68 catheter over a comparable period.

Results: We treated 47 patients using the React 68 catheter using either aspiration alone or a combination of aspiration and stent retriever technique. The catheter was used in a variety of circumstances including proximal and distal occlusions involving the anterior and posterior circulation. Modified TICI 2b-3 was achieved in 45 of the 47 patients. The React 68 was comparable to the ACE 68 by all performance measures.

Conclusion: The React 68 catheter is a large-bore reperfusion catheter with trackability suitable for use in direct aspiration for recanalization of emergent large vessel occlusion.

Keywords: Emergent large vessel occlusion; aspiration; thrombectomy.

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Figures

Figure 1.
Figure 1.
Elderly patient presenting with acute left hemiparesis. (a) Axial MIPs from CTA demonstrate a right M1 occlusion with good collateral opacification. (b) Initial transfemoral catheter angiography confirms the right M1 occlusion. (c) Complete recanalization and reperfusion (mTICI 3) after two aspiration attempts.
Figure 2.
Figure 2.
Elderly patient presents with left hemiparesis. (a) Axial MIPs from CTA demonstrate a proximal right M2 occlusion. (b) Initial transfemoral catheter angiography confirms a proximal right M2 occlusion. (c) Complete recanalization of the proximal occlusion and good distal reperfusion (mTICI 2b) after three thrombectomy passes.
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References

    1. Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015; 372: 1019–1030. - PubMed
    1. Jovin TG, Chamorro A, Cobo E, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015; 372: 2296–2306. - PubMed
    1. Saver JL, Goyal M, Bonafe A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015; 372: 2285–2295. - PubMed
    1. Berkhemer OA, Fransen PS, Beumer D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015; 372: 11–20. - PubMed
    1. Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015; 372: 1009–1018. - PubMed

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