Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Nov 1;463(2):357-61.
doi: 10.1016/0006-8993(88)90410-6.

Lamina-specific arrangement of astrocytic gliosis and senile plaques in Alzheimer's disease visual cortex

T G Beach  1 , E G McGeer
Affiliations

Lamina-specific arrangement of astrocytic gliosis and senile plaques in Alzheimer's disease visual cortex

T G Beach et al. Brain Res. .

Abstract

Alzheimer's disease (AD) visual cortex (area 17) was investigated using stains for plaques and tangles (Bielschowsky, thioflavine S) and gliosis (GFAP immunoperoxidase). Pathology was heaviest in layers II, III, IVa and IVc. Of especial interest was a thin line of plaques and astrocytic gliosis at the lower margin of layer IVc. These results could provide an insight into the pathogenesis of AD, and suggest that patients with AD may have specific visual deficits.

PubMed Disclaimer

Publication types

Substances

LinkOut - more resources