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Case Reports
. 2020 Jan 21;13(1):e231514.
doi: 10.1136/bcr-2019-231514.

Postoperative Horner's syndrome following excision of incidental cervical ganglioneuroma during hemithyroidectomy and parathyroid gland exploration

Affiliations
Case Reports

Postoperative Horner's syndrome following excision of incidental cervical ganglioneuroma during hemithyroidectomy and parathyroid gland exploration

David McCrory et al. BMJ Case Rep. .

Abstract

This 49-year-old woman was referred to ear, nose and throat (ENT) with primary hyperparathyroidism. Imaging studies failed to localise the adenoma so she required four-gland parathyroid exploration. She also required diagnostic left hemithyroidectomy as she had a U3 nodule with multiple insufficient fine needle aspirations (FNAs). Intraoperatively, the left thyroidectomy proceeded uneventfully. No convincing left inferior parathyroid gland was identified however palpation revealed a 1 cm mass just medial to carotid artery. This was excised as probable ectopic parathyroid gland. She was discharged two days later. Thirteen days postoperatively she attended Eye Casualty with a left-sided Horner's syndrome. A CT angio of aortic arch was normal. She was reviewed at ENT outpatients. Histopathology report of the expected ectopic parathyroid gland returned as benign ganglioneuroma, likely arising from her left sympathetic chain. Horner's syndrome is a common side effect from excision of ganglioneuromas, but an incredibly rare side effect from thyroid or parathyroid surgery.

Keywords: ear, nose and throat/otolaryngology; head and neck surgery; otolaryngology/ENT; thyroid disease.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Nuclear Medicine (NM) parathyroid SPECT-CT scan. Line measuring 14.2 mm left thyroid nodule.
Figure 2
Figure 2
Annotated NM parathyroid SPECT-CT. Carotid artery in red, ganglioneuroma in green, musculature in blue. Note ganglioneuroma indenting the musculature.

References

    1. Katılmış H, Öztürkcan S, Adadan I, et al. . Cervical ganglioneuroma. Int J Pediatr Otorhinolaryngol Extra 2006;1:157–9. 10.1016/j.pedex.2006.04.006 - DOI
    1. Ma J, Liang L, Liu H. Multiple cervical ganglioneuroma: a case report and review of the literature. Oncol Lett 2012;4:509–12. 10.3892/ol.2012.767 - DOI - PMC - PubMed
    1. Cavanaugh DA, Jawahar A, Harper J, et al. . Cervical ganglioneuroma in an adult man: case report and literature review of a rare occurrence. J La State Med Soc 2010;162:218–21. - PubMed
    1. Califano L, Zupi A, Mangone GM, et al. . Cervical ganglioneuroma: report of a case. Otolarynology Head Neck Surg 2001;124:115–6. - PubMed
    1. Geoerger B, Hero B, Harms D, et al. . Metabolic activity and clinical features of primary ganglioneuromas. Cancer 2001;91:1905–13. 10.1002/1097-0142(20010515)91:10<1905::AID-CNCR1213>3.0.CO;2-4 - DOI - PubMed

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