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. 2018 Jul;16(3):292-298.
doi: 10.1176/appi.focus.20180007. Epub 2018 Jul 16.

An Additive Mix? Acute Urinary Retention in a Patient With Benign Prostatic Hyperplasia Treated With Suboxone, Lurasidone, and Trazodone

Benjamin Kahn  1 , Mina Boazak  1 , James Ragazino  1 , R Craig Sineath  1 , Troy Kapral  1
Affiliations

An Additive Mix? Acute Urinary Retention in a Patient With Benign Prostatic Hyperplasia Treated With Suboxone, Lurasidone, and Trazodone

Benjamin Kahn et al. Focus (Am Psychiatr Publ). 2018 Jul.

Abstract

Treatment of psychiatric patients is frequently complicated by medical comorbidities, complex pharmacologic regimens, and side effects occurring secondarily to those regimens. Acute urinary retention is an infrequently discussed side effect of such regimens. This report describes the development of acute urinary retention (AUR) in a 60-year-old man with a history of benign prostatic hyperplasia. The patient developed AUR during treatment with combination buprenorphine/naloxone, trazodone, and lurasidone. We discuss the potential relationship of these agents to the development of this patient's AUR, the complicated neurochemical dynamic of the voiding process, and the pathologic consequences that psychotropic agents can have on that process.

Keywords: Buprenorphine; lurasidone; trazodone; urinary hesitancy; urinary retention.

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Figures

FIGURE 1.
FIGURE 1.
Patient Medication Schedule During Hospital Stay
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