Advances and Impact of Antioxidant Hydrogel in Chronic Wound Healing
- PMID: 31977162
- DOI: 10.1002/adhm.201901502
Advances and Impact of Antioxidant Hydrogel in Chronic Wound Healing
Abstract
The accelerating and thorough treatment of chronic wounds still represents a major unmet medical need owing to the complex symptoms resulting from metabolic disorder of the wound microenvironment. Although numerous strategies and bioactive hydrogels are developed, an effective and widely used method of chronic wound treatment remains a bottleneck. With the aim to accelerate chronic wound healing, many hydrogel dressings with antioxidant functions have emerged and are proven to accelerate wound healing, especially for chronic wound repair. The new strategy in chronic wound treatment brought by antioxidant hydrogels is of great significance to human health. Here, the application of antioxidant hydrogels in the repair of chronic wounds is discussed systematically, aiming to provide an important theoretical reference for the further breakthrough of chronic wound healing.
Keywords: antioxidants; chronic wound healing; hydrogels.
© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Similar articles
-
Design Considerations for Hydrogel Wound Dressings: Strategic and Molecular Advances.Tissue Eng Part B Rev. 2020 Jun;26(3):230-248. doi: 10.1089/ten.TEB.2019.0281. Epub 2020 Feb 28. Tissue Eng Part B Rev. 2020. PMID: 31928151 Review.
-
Hydrogel Wound Dressings Accelerating Healing Process of Wounds in Movable Parts.Int J Mol Sci. 2024 Jun 15;25(12):6610. doi: 10.3390/ijms25126610. Int J Mol Sci. 2024. PMID: 38928316 Free PMC article. Review.
-
Functional carbohydrate-based hydrogels for diabetic wound therapy.Carbohydr Polym. 2023 Jul 15;312:120823. doi: 10.1016/j.carbpol.2023.120823. Epub 2023 Mar 20. Carbohydr Polym. 2023. PMID: 37059550 Review.
-
Advances of hydrogel dressings in diabetic wounds.Biomater Sci. 2021 Mar 10;9(5):1530-1546. doi: 10.1039/d0bm01747g. Biomater Sci. 2021. PMID: 33433534 Review.
-
Recent Progress of Highly Adhesive Hydrogels as Wound Dressings.Biomacromolecules. 2020 Oct 12;21(10):3966-3983. doi: 10.1021/acs.biomac.0c01069. Epub 2020 Sep 30. Biomacromolecules. 2020. PMID: 32960043 Review.
Cited by
-
Bioshell Calcium Oxide (BiSCaO) Ointment for the Disinfection and Healing of Pseudomonas aeruginosa-Infected Wounds in Hairless Rats.Int J Mol Sci. 2020 Jun 11;21(11):4176. doi: 10.3390/ijms21114176. Int J Mol Sci. 2020. PMID: 32545309 Free PMC article.
-
Beneficial Effects of Phenolic Compounds on Gut Microbiota and Metabolic Syndrome.Int J Mol Sci. 2021 Apr 2;22(7):3715. doi: 10.3390/ijms22073715. Int J Mol Sci. 2021. PMID: 33918284 Free PMC article. Review.
-
Cellular Interaction of Human Skin Cells towards Natural Bioink via 3D-Bioprinting Technologies for Chronic Wound: A Comprehensive Review.Int J Mol Sci. 2022 Jan 1;23(1):476. doi: 10.3390/ijms23010476. Int J Mol Sci. 2022. PMID: 35008902 Free PMC article. Review.
-
Double cross-linked graphene oxide hydrogel for promoting healing of diabetic ulcers.Front Chem. 2024 Feb 22;12:1355646. doi: 10.3389/fchem.2024.1355646. eCollection 2024. Front Chem. 2024. PMID: 38456184 Free PMC article.
-
Mechanism of the effect of Piper crocatum extract on wound healing of Wistar rats post-excision mammary tumor based on IL-10 level, TGF-β1 expression, VEGF expression, Collagen density, and clinical features.Open Vet J. 2025 Mar;15(3):1264-1278. doi: 10.5455/OVJ.2025.v15.i3.18. Epub 2025 Mar 31. Open Vet J. 2025. PMID: 40276181 Free PMC article.
References
-
- L. Shi, X. Liu, W. Wang, L. Jiang, S. Wang, Adv. Mater. 2019, 31, 1804187.
-
- J. Zhou, D. Yao, Z. Qian, S. Hou, L. Li, A. T. A. Jenkins, Y. Fan, Biomaterials 2018, 161, 11.
-
- C. Helary, A. Abed, G. Mosser, L. Louedec, D. Letourneur, T. Coradin, M. G. Guille, A. M. Pelle, Biomater. Sci. 2015, 3, 2.
-
- S. Ye, L. Jiang, J. Wu, C. Su, C. Huang, X. Liu, W. Shao, ACS Appl. Mater. Interfaces 2018, 10, 5862.
-
- T. Hakkarainen, R. Koivuniemi, M. Kosonen, C. Escobedo-Lucea, A. Sanz-Garcia, J. Vuola, J. Valtonen, P. Tammela, A. Mäkitie, K. Luukko, M. Yliperttula, H. Kavola, J. Controlled Release 2016, 244, 292.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical