Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1988 Oct;148(1):37-9.
doi: 10.1007/BF00441811.

Clastogen-induced fragility may differentiate pancytopenia of congenital dyskeratosis from Fanconi anaemia

A Schneider  1 , U Mayer, E Gebhart, D Harms, J Gromball, U Glöckel, J D Beck
Affiliations
Case Reports

Clastogen-induced fragility may differentiate pancytopenia of congenital dyskeratosis from Fanconi anaemia

A Schneider et al. Eur J Pediatr. 1988 Oct.

Abstract

A male infant is reported with congenital dyskeratosis and pancytopenia Zinsser-Engman-Cole. The bone marrow pathology showed similarities to Fanconi anaemia. Ophthalmological complications were vitreous haemorrhage, haemorrhagic cataracta complicata and glaucoma. Spontaneous and diepoxybutane-induced chromosomal fragility was within the range of normal cells but was elevated through induction with 4-nitroquinoline-oxide. These findings are contrasted with those of Fanconi anaemia.

PubMed Disclaimer

References

    1. Z Kinderheilkd. 1964 Dec 1;91:297-337 - PubMed
    1. Arch Dermatol. 1978 Nov;114(11):1667-71 - PubMed
    1. Pediatrics. 1983 Apr;71(4):603-9 - PubMed
    1. Am J Dis Child. 1972 Nov;124(5):701-4 - PubMed
    1. Pediatr Radiol. 1982;12 (1):31-6 - PubMed

Publication types

LinkOut - more resources