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. 2021 Feb;23(2):117-122.
doi: 10.1080/10286020.2019.1709450. Epub 2020 Jan 24.

Asperpenes D and E from the fungus Aspergillus sp. SCS-KFD66 isolated from a bivalve mollusk, Sanguinolaria chinensis

Chang-Liang An  1   2 , Fan-Dong Kong  1 , Yan Li  3 , Qing-Yun Ma  1 , Qing-Yi Xie  1 , Jing-Zhe Yuan  1 , Li-Man Zhou  1 , Hao-Fu Dai  1 , Zhi-Fang Yu  2 , You-Xing Zhao  1
Affiliations

Asperpenes D and E from the fungus Aspergillus sp. SCS-KFD66 isolated from a bivalve mollusk, Sanguinolaria chinensis

Chang-Liang An et al. J Asian Nat Prod Res. 2021 Feb.

Abstract

Two new compounds named asperpenes D (1) and E (2) were isolated from the marine-derived fungus Aspergillus sp. SCS-KFD66. Their structures were determined on the basis of spectroscopic methods. Compound 2 represents the first natural product bearing a 2-substituted-5-oxo-4-phenyl-2,5-dihydrofuran-3-carboxylic acid skeleton. All the compounds were tested for enzyme inhibitory activity against AChE and α-glucosidase and DPPH radical scavenging activity, respectively. [Formula: see text].

Keywords: Aspergillus sp.; Marine-derived fungus; secondary metabolites.

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