Simplified frailty assessment tools: are we really capturing frailty or something else?

Smith Giri¹, Grant Williams², Ashley Rosko³, Shakira J Grant⁴, Hira S Mian⁵, Sascha Tuchman⁶, Sonja Zweegman⁷, Tanya M Wildes⁸

Affiliations

¹ Institute for Cancer Outcomes and Survivorship, Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, 1600 7th Avenue South, Lowder 500, Birmingham, AL, 35294, USA. smithgiri@uabmc.edu.
² Institute for Cancer Outcomes and Survivorship, Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, 1600 7th Avenue South, Lowder 500, Birmingham, AL, 35294, USA.
³ Division of Hematology/Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
⁴ Division of Hematology/Oncology, The University of Washington/Fred Hutchinson Cancer Center, Seattle, WA, USA.
⁵ Department of Oncology, McMaster University, Hamilton, ON, Canada.
⁶ Division of Hematology/Oncology, The University of North Carolina-Chapel Hill Comprehensive Cancer Center, Chapel Hill, NC, USA.
⁷ Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands.
⁸ Division of Medical Oncology, Washington University School of Medicine, St Louis, MO, USA.

PMID: 31980732
PMCID: PMC7332387
DOI: 10.1038/s41375-020-0712-5

Comment

Simplified frailty assessment tools: are we really capturing frailty or something else?

Smith Giri et al. Leukemia. 2020 Jul.

. 2020 Jul;34(7):1967-1969.

doi: 10.1038/s41375-020-0712-5. Epub 2020 Jan 24.

Authors

Smith Giri¹, Grant Williams², Ashley Rosko³, Shakira J Grant⁴, Hira S Mian⁵, Sascha Tuchman⁶, Sonja Zweegman⁷, Tanya M Wildes⁸

Affiliations

¹ Institute for Cancer Outcomes and Survivorship, Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, 1600 7th Avenue South, Lowder 500, Birmingham, AL, 35294, USA. smithgiri@uabmc.edu.
² Institute for Cancer Outcomes and Survivorship, Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, 1600 7th Avenue South, Lowder 500, Birmingham, AL, 35294, USA.
³ Division of Hematology/Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
⁴ Division of Hematology/Oncology, The University of Washington/Fred Hutchinson Cancer Center, Seattle, WA, USA.
⁵ Department of Oncology, McMaster University, Hamilton, ON, Canada.
⁶ Division of Hematology/Oncology, The University of North Carolina-Chapel Hill Comprehensive Cancer Center, Chapel Hill, NC, USA.
⁷ Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands.
⁸ Division of Medical Oncology, Washington University School of Medicine, St Louis, MO, USA.

PMID: 31980732
PMCID: PMC7332387
DOI: 10.1038/s41375-020-0712-5

No abstract available

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Conflict of interest statement

Conflict of interest SZ reports research funding from Takeda, Janssen, and Celgene; TW reports research funding from Janssen and consultancy with Carevive system; none of the other authors have relevant conflicts of interest to disclose.

Comment on

A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
Facon T, Dimopoulos MA, Meuleman N, Belch A, Mohty M, Chen WM, Kim K, Zamagni E, Rodriguez-Otero P, Renwick W, Rose C, Tempescul A, Boyle E, Manier S, Attal M, Moreau P, Macro M, Leleu X, Lorraine Chretien M, Ludwig H, Guo S, Sturniolo M, Tinel A, Silvia Monzini M, Costa B, Houck V, Hulin C, Yves Mary J. Facon T, et al. Leukemia. 2020 Jan;34(1):224-233. doi: 10.1038/s41375-019-0539-0. Epub 2019 Aug 19. Leukemia. 2020. PMID: 31427722 Free PMC article. Clinical Trial.

References

1. Facon T, Dimopoulos MA, Meuleman N, Belch A, Mohty M, Chen WM, et al. A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial. Leukemia. 2019;34:224–33. - PMC - PubMed
1. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146–56. - PubMed
1. Rockwood K, Mitnitski A. Frailty in relation to the accumulation of deficits. J Gerontol A Biol Sci Med Sci. 2007;62:722–7. - PubMed
1. Rodriguez-Manas L, Feart C, Mann G, Vina J, Chatterji S, Chodzko-Zaiko W, et al. Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci. 2013;68:62–7. - PMC - PubMed
1. Buta BJ, Walston JD, Godino JG, Park M, Kalyani RR, Xue QL, et al. Frailty assessment instruments: systematic characterization of the uses and contexts of highly-cited instruments. Ageing Res Rev. 2016;26:53–61. - PMC - PubMed

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Simplified frailty assessment tools: are we really capturing frailty or something else?

Affiliations

Simplified frailty assessment tools: are we really capturing frailty or something else?

Authors

Affiliations

Conflict of interest statement

Comment on

References

Publication types

MeSH terms

Grants and funding

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Medical