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Review
. 2020 Jan 27;12(1):6-9.
doi: 10.4254/wjh.v12.i1.6.

Concise review of machine perfusion in liver transplantation

Affiliations
Review

Concise review of machine perfusion in liver transplantation

Chirag S Desai et al. World J Hepatol. .

Abstract

With the advances and clinical growth in liver transplantation over the last four decades the focus on expanding deceased donor organs has been in need of scientific research. In the past ten years several researchers have looked at the domain of machine perfusion as it applies to deceased donor livers. The following review focuses on the clinical trials and recent advances that will likely have the earliest entrance into the clinical arena.

Keywords: Ex vivo perfusion; Ischemia reperfusion; Liver transplantation; Machine perfusion; Organ preservation.

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Conflict of interest statement

Conflict-of-interest statement: The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Schematic design of machine perfusion. Demonstrating system circulation and pumps with the ability to oxygenate the perfusate. Flow comes into the liver through the portal vein with bile collected separately.

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