Toward nanoscale localization of memory engrams in Drosophila

Abstract

The Mushroom Body (MB) is the primary location of stored associative memories in the Drosophila brain. We discuss recent advances in understanding the MB's neuronal circuits made using advanced light microscopic methods and cell-type-specific genetic tools. We also review how the compartmentalized nature of the MB's organization allows this brain area to form and store memories with widely different dynamics.

Keywords: Memory genes; associative learning; dopamine; memory engrams; mushroom body.