Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Feb 12;1(6058):420-2.
doi: 10.1136/bmj.1.6058.420.

Successful bone marrow transplant for Fanconi's anaemia

A J Barrett, W D Brigden, J R Hobbs, K Hugh-Jones, J G Humble, D C James, S Retsas, T R Rogers, S Selwyn, P Sneath, J G Watson

Successful bone marrow transplant for Fanconi's anaemia

A J Barrett et al. Br Med J. .

Abstract

A 15-year-old boy with Fanconi's anaemia, who required four units of blood each month, received a bone marrow graft from his 9-year-old brother, who has HLA identical and compatible on mixed lymphocyte reaction. Considerable immunosuppression was used and bacterial infection was prevented by vigorous decontamination in a Vickers-Trexler isolator. After the graft the patient's blood counts remained satisfactory for nine months, but it took six months before qualitative immune function was normal.

PubMed Disclaimer

References

    1. Blood. 1974 Feb;43(2):157-80 - PubMed
    1. Blood. 1974 Jul;44(1):1-18 - PubMed
    1. Br Med J. 1975 Dec 6;4(5996):549-52 - PubMed
    1. J Immunol Methods. 1976;10(4):367-78 - PubMed
    1. Clin Exp Immunol. 1973 Jul;14(3):457-67 - PubMed

LinkOut - more resources