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Review
. 2019 Oct-Dec;15(4):267-273.
doi: 10.14797/mdcj-15-4-267.

Prevention and Treatment of Chemotherapy-Induced Cardiotoxicity

Monica Samuel Avila  1 , Suellen Rodrigues Rangel Siqueira  1 , Silvia Moreira Ayub Ferreira  1 , Edimar Alcides Bocchi  1
Affiliations
Review

Prevention and Treatment of Chemotherapy-Induced Cardiotoxicity

Monica Samuel Avila et al. Methodist Debakey Cardiovasc J. 2019 Oct-Dec.

Abstract

Recent decades have seen an increase in survival rates for cancer patients, partially explained by earlier diagnoses and new chemotherapeutic agents. However, chemotherapy may be associated with adverse cardiovascular events, including hypertension and pulmonary hypertension, supraventricular and ventricular arrhythmias, cardiomyopathy, and other forms of cardiovascular disease. For patients, the benefits of chemotherapy may be partially obfuscated by deleterious effects on the cardiovascular system, resulting in a significant increase in morbidity and mortality. In this article, we review strategies for prevention and treatment of chemotherapy-related cardiotoxicity.

Keywords: anthracyclines; cancer; cardio-oncology; cardiotoxicity; chemotherapy; heart disease; prevention; treatment.

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Conflict of interest statement

Conflict of Interest Disclosure: The authors have completed and submitted the Methodist DeBakey Cardiovascular Journal Conflict of Interest Statement and none were reported.

Figures

Figure 1.
Figure 1.
Sequential levels of troponin I during chemotherapy treatment.
See this image and copyright information in PMC

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