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. 2019 Jan-Jun;9(1):23-26.
doi: 10.5005/jp-journals-10018-1291.

Association of Cirrhosis and Cardiomyopathy

Burcu Sezgin  1 , Cigdem Cindoglu  2 , Ahmet Uyanikoglu  3 , Necati Yenice  3
Affiliations

Association of Cirrhosis and Cardiomyopathy

Burcu Sezgin et al. Euroasian J Hepatogastroenterol. 2019 Jan-Jun.

Abstract

Introduction: We investigated association of pro-BNP, troponin-I, electrocardiography (ECG) and echocardiography (ECHO) during diagnosis and identification of cirrhotic cardiomyopathy in cirrhotic patients.

Materials and methods: Patients were divided into three groups as; compensated cirrhotic patients (group 1, n= 30), decompensated cirrhotic (group 2, n = 30) and control group (group 3, n = 30). ECHO, and ECG were performed, and troponin-I and levels of pro-BNP were analyzed.

Results: Average age of group 1 was 46.36 ± 16 years (range 19-86), 60% were female; group 2 was 57.03 ± 13.54 years (range 22-89), 56% female; and group 3 was 49.13 ± 0.95 years (range 18-80), 56% female. A significant increase in QTc was detected in compensated cirrhotic patients compared to the control group (p <0.05). Pro-BNP levels were significantly higher (p <0.05) in the compensated cirrhotic group compared to the control group. The levels of pro-BNP were also significantly higher in the decompensated cirrhotic group compared compensated cirrhosis group and control group (p <0.001).

Conclusion: The increase of pro-BNP levels with severity of the disease in cirrhotic patients and the prolongation of QTc interval supports an association between these factors with cardiomyopathy.

How to cite this article: Sezgin B, Cindoglu C, et al. Association of Cirrhosis and Cardiomyopathy. Euroasian J Hepatogastroenterol 2019;9(1):23-26.

Keywords: Cardiomyopathy; Cirrhosis; Pro-BNP; QT prolongation; Troponin-I.

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Conflict of interest statement

Source of support: This research, supported Harran University Research Fund Project 12118 Conflict of interest: None

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