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Case Reports
. 1988 Dec;158(6):1193-7.
doi: 10.1093/infdis/158.6.1193.

Characterization of a sequence of human T cell leukemia virus type I from a patient with chronic progressive myelopathy

S Kwok  1 , D Kellogg, G Ehrlich, B Poiesz, S Bhagavati, J J Sninsky
Affiliations
Case Reports

Characterization of a sequence of human T cell leukemia virus type I from a patient with chronic progressive myelopathy

S Kwok et al. J Infect Dis. 1988 Dec.

Abstract

DNA from peripheral blood mononuclear cells of individuals with chronic progressive myelopathy (CPM) were extensively analyzed for the presence of human T cell leukemia virus (HTLV) type I-like sequences by using the polymerase chain reaction. The DNA samples were amplified with oligonucleotides from three separate regions of HTLV viral genomes. A portion of the amplified viral genome from a representative patient was sequenced after molecular cloning into bacteriophage M13. Sequence data indicate that HTLV type I and not a related virus is associated with CPM.

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