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. 2020 Feb;180(1):247-256.
doi: 10.1007/s10549-020-05544-2. Epub 2020 Jan 27.

Patient-reported outcome after oncoplastic breast surgery compared with conventional breast-conserving surgery in breast cancer

Michael Rose  1   2 , Henry Svensson  3   4 , Jürgen Handler  5 , Ute Hoyer  6 , Anita Ringberg  3   4 , Jonas Manjer  3   7
Affiliations

Patient-reported outcome after oncoplastic breast surgery compared with conventional breast-conserving surgery in breast cancer

Michael Rose et al. Breast Cancer Res Treat. 2020 Feb.

Abstract

Introduction: Oncoplastic breast surgery (OBS) has developed as an extension of breast-conserving surgery (BCS) in an effort to improve esthetic and functional outcome following surgery for breast cancer. The aim of the present study was to evaluate the possible benefits of OBS, as compared with BCS, with regard to health-related quality of life (HRQoL), using patient-reported outcome measures (PROMs).

Patients and methods: Patients treated with OBS (n = 200) and BCS (n = 1304) in the period 1 January 2008 to 31 December 2013 were identified in a research database and in the Danish Breast Cancer Cooperative Group (DBCG) registry. Data on patient, tumor, and treatment characteristics were retrieved from the DBCG registry. Patients were sent a survey including the Breast-Q™ BCT postoperative module and a study-specific questionnaire (SSQ) in 2016. A good outcome in the Breast-Q module was defined as above the median. OBS was compared to BCS using a logistic regression analysis, and then adjusted for potential confounders, yielding odds ratios (OR) with 95% confidence intervals.

Results: There was a statistically significant better outcome considering the HRQoL domain "Psychosocial Well-being " for patients treated with OBS as compared with BCS (OR 2.15: 1.25-3.69). No statistically significant differences were found for the domains "Physical Well-being" (0.83: 0.50-1.39), "Satisfaction with Breast" (0.95: 0.57-1.59), or "Sexual Well-being" (1.42: 0.78-2.58).

Conclusion: The present study indicates better outcomes of HRQoL for breast cancer patients treated with OBS as compared to patients treated with BCS. There was no increase in physical discomfort among OBS patients despite more extensive surgery.

Keywords: Breast cancer; Breast conserving surgery; Breast-Q; Oncoplastic breast surgery; Patient-reported outcome.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Breast-Conserving Surgery (BCS) and Oncoplastic Breast Surgery (OBS) cohorts
See this image and copyright information in PMC

Comment in

References

    1. Wolmark N, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347:1233–1241. doi: 10.1056/NEJMoa022152. - DOI - PubMed
    1. Blichert-Toft M, et al. Long-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-Year follow-up of the Danish randomized DBCG-82TM protocol. Acta Oncol. 2008;47:672–681. doi: 10.1080/02841860801971439. - DOI - PubMed
    1. Christiansen P, et al. Breast conserving surgery versus mastectomy: overall and relative survival—a population based study by the Danish Breast Cancer Cooperative Group (DBCG ) Supplementary material. Acta Oncol. 2017;57:1–3. - PubMed
    1. Weber WP, et al. Standardization of oncoplastic breast conserving surgery. Eur J Surg Oncol. 2017;43:1236–1243. doi: 10.1016/j.ejso.2017.01.006. - DOI - PubMed
    1. Berry MG, Fitoussi AD, Curnier A, Couturaud B, Salmon RJ. Oncoplastic breast surgery: a review and systematic approach. J Plast Reconstr Aesth Surg. 2010;63:1233–1243. doi: 10.1016/j.bjps.2009.05.006. - DOI - PubMed