Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Apr;44(2):47-52.
doi: 10.1192/bjb.2019.92.

Online mood monitoring in treatment-resistant depression: qualitative study of patients' perspectives in the NHS

Affiliations

Online mood monitoring in treatment-resistant depression: qualitative study of patients' perspectives in the NHS

Emma Incecik et al. BJPsych Bull. 2020 Apr.

Abstract

Aims and method: True Colours is an automated symptom monitoring programme used by National Health Service psychiatric services. This study explored whether patients with unipolar treatment-resistant depression (TRD) found this a useful addition to their treatment regimes. Semi-structured qualitative interviews were conducted with 21 patients with TRD, who had engaged in True Colours monitoring as part of the Lithium versus Quetiapine in Depression study. A thematic analysis was used to assess participant experiences of the system.

Results: Six main themes emerged from the data, the most notable indicating that mood monitoring increased patients' insight into their disorder, but that subsequent behaviour change was absent.

Clinical implications: Patients with TRD can benefit from mood monitoring via True Colours, making it a worthwhile addition to treatment. Further development of such systems and additional support may be required for patients with TRD to experience further benefits as reported by other patient groups.

Keywords: Treatment-resistant depression; True Colours; major depression; mood monitoring; qualitative research.

PubMed Disclaimer

Conflict of interest statement

Declaration of interest: In the past 3 years, A.J.C. has received honoraria for speaking from Astra Zeneca and Lundbeck; honoraria for consulting from Allergan, Janssen, Livanova and Lundbeck; support for conference attendance from Janssen and research grant support from the Medical Research Council (MRC), Wellcome and National Institute for Health Research (NIHR). S.L.H. has received grant support from Wellcome Trust, NIHR, Department of Health and Social Care, MRC, Guy's and St Thomas' Charity, and the Economic and Social Research Council. J.R.G. led the conception of True Colours and has overseen its implementation in routine clinical practice and research studies. He is an NIHR senior investigator and has received research funding from MRC, Wellcome and NIHR. No other authors report any conflicts of interest, although E.I. conducted some of the interviews as part of her master's dissertation project.

References

    1. Fekadu A, Wooderson SC, Markopoulo K, Donaldson C, Papadopoulos A, Cleare AJ. What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies. J Affect Disord 2009; 116(1): 4–11. - PubMed
    1. Tsanas A, Saunders KEA, Bilderbeck AC, Palmius N, Osipov M, Clifford GD, et al. Daily longitudinal self-monitoring of mood variability in bipolar disorder and borderline personality disorder. J Affect Disord 2016; 205: 225–33. - PMC - PubMed
    1. Malik A, Goodwin GM, Holmes EA. Contemporary approaches to frequent mood monitoring in bipolar disorder. J Exp Psychopathol 2012; 3(4): 572–81. - PMC - PubMed
    1. Holmes EA, Bonsall MB, Hales SA, Mitchell H, Renner F, Blackwell SE, et al. Applications of time-series analysis to mood fluctuations in bipolar disorder to promote treatment innovation: a case series. Transl Psychiatry 2016; 6(1): e720. - PMC - PubMed
    1. Bipolar Disorder Research Network (BDRN).True Colours. BDRN, 2020. (http://bdrn.org/research/true-colours/).