Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2020 Mar;31(3):429-446.
doi: 10.1007/s00198-020-05308-0. Epub 2020 Jan 28.

Interventions to improve osteoporosis care: a systematic review and meta-analysis

J Martin  1   2 , M Viprey  1   2 , B Castagne  1   3 , B Merle  4 , C Giroudon  5 , R Chapurlat  4   6 , A-M Schott  7   8
Affiliations
Meta-Analysis

Interventions to improve osteoporosis care: a systematic review and meta-analysis

J Martin et al. Osteoporos Int. 2020 Mar.

Abstract

Osteoporosis (OP) is a major public health concern, but still OP care does not meet guidelines. Interventions have been developed to improve appropriate OP management. The objective of the present study was to systematically review the current literature to ascertain the efficacy of interventions to improve OP care and characterize interventions taking into account elements related to their potential cost and feasibility. Studies published from 2003 to 2018 were retrieved from PubMed/MEDLINE, Science Direct, Web of Science, Cochrane, and Wiley Online Library databases. Screening of references and quality assessment were independently performed by two reviewers. We classified interventions into three types according to the target of the intervention: health system (structural interventions), healthcare professional (HCP), and patient. Meta-analysis was performed by type of intervention and their effect on two outcomes: prescription of BMD measurement and prescription of OP therapy. A total of 4268 records were screened; 32 studies were included in the qualitative analysis and 29 studies in the quantitative analysis. Structural interventions strongly and significantly improved prescription of BMD measurement (OR = 9.99, 95% CI 2.05; 48.59) and treatment prescription (OR = 3.82, 95% CI 2.16; 6.75). The impact of HCP-centered interventions on BMD measurement prescription did not reach statistical significance (OR = 2.19, 95% CI 0.84; 5.73) but significantly improved treatment prescription (OR = 3.82, 95% CI 2.16; 6.75). Interventions involving patients significantly improved the prescription of BMD measurement (OR = 2.16, 95% CI 1.62; 2.89) and treatment prescription (OR = 1.70, 95% CI 1.35; 2.14). Interventions to improve OP management had a significant positive impact on prescription of BMD measurement but a more limited impact on treatment prescription.

Keywords: Bone mineral density; Care; Intervention; Osteoporosis; Therapy prescription.

PubMed Disclaimer

References

    1. Endocr Pract. 2016 Sep;22(9):1111-8 - PubMed
    1. PLoS Med. 2009 Jul 21;6(7):e1000097 - PubMed
    1. J Clin Densitom. 2015 Apr-Jun;18(2):150-6 - PubMed
    1. Medicine (Baltimore). 2017 Dec;96(48):e9012 - PubMed
    1. Arch Osteoporos. 2016;11:10 - PubMed

LinkOut - more resources