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. 2020 Jun;29(6):1675-1683.
doi: 10.1007/s11136-020-02425-5. Epub 2020 Jan 28.

Mild cognitive impairment and quality of life in the oldest old: a closer look

Felix S Hussenoeder #  1 , Ines Conrad  2 , Susanne Roehr  2 , Angela Fuchs  3 , Michael Pentzek  3 , Horst Bickel  4 , Edelgard Moesch  4 , Siegfried Weyerer  5 , Jochen Werle  5 , Birgitt Wiese  6 , Silke Mamone  6 , Christian Brettschneider  7 , Kathrin Heser  8 , Luca Kleineidam  8 , Hanna Kaduszkiewicz  9 , Marion Eisele  10 , Wolfgang Maier  11 , Michael Wagner  8   12 , Martin Scherer  10 , Hans-Helmut König #  7 , Steffi G Riedel-Heller  2
Affiliations

Mild cognitive impairment and quality of life in the oldest old: a closer look

Felix S Hussenoeder et al. Qual Life Res. 2020 Jun.

Abstract

Purpose: Mild cognitive impairment (MCI) is a widespread phenomenon, especially affecting older individuals. We will analyze in how far MCI affects different facets of quality of life (QOL).

Methods: We used a sample of 903 participants (110 with MCI) from the fifth follow-up of the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe), a prospective longitudinal study, to analyze the effects of MCI on different facets of the WHOQOL-OLD. We controlled for age, gender, marital status, education, living situation, daily living skills, and the ability to walk, see, and hear.

Results: Univariate analyses showed that individuals with MCI exhibited lower QOL with regard to the facets autonomy; past, present, and future activities; social participation; and intimacy, but less fears related to death and dying. No significant difference was shown with regard to the facet sensory abilities. In multivariate analyses controlling for age, gender, marital status, education, living situation, daily living skills, and the ability to walk, see and hear, MCI-status was significantly associated with QOL in the facet autonomy.

Conclusion: Effects of MCI go beyond cognition and significantly impact the lives of those affected. Further research and practice will benefit from utilizing specific facets of QOL rather than a total score.

Keywords: MCI; Older people; Quality of life; WHOQOL-OLD.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Process of sample selection
See this image and copyright information in PMC

References

    1. Barberger-Gateau P, Commenges D, Gagnon M, Letenneur L, Sauvel C, Dartigues JF. Instrumental activities of daily living as a screening tool for cognitive impairment and dementia in elderly community dwellers. Journal of the American Geriatrics Society. 1992;40(11):1129–1134. doi: 10.1111/j.1532-5415.1992.tb01802.x. - DOI - PubMed
    1. Campbell NL, Unverzagt F, LaMantia MA, Khan BA, Boustani MA. Risk factors for the progression of mild cognitive impairment to dementia. Clinics in Geriatric Medicine. 2013;29(4):873–893. doi: 10.1016/j.cger.2013.07.009. - DOI - PMC - PubMed
    1. Clement-Carbonell V, Ferrer-Cascales R, Ruiz-Robledillo N, Rubio-Aparicio M, Portilla-Tamarit I, Cabañero-Martínez MJ. Differences in autonomy and health-related quality of life between resilient and non-resilient individuals with mild cognitive impairment International. Journal of Environmental Research and Public Health. 2019 doi: 10.3390/ijerph16132317. - DOI - PMC - PubMed
    1. Conrad I, Matschinger H, Kilian R, Riedel-Heller SG. WHOQOL-OLD und WHOQOL-BREF : Manual : Handbuch für die deutschsprachigen Versionen der WHO-Instrumente zur Erfassung der Lebensqualität im Alter. 1. Göttingen: Hogrefe; 2016.
    1. Conrad I, Matschinger H, Riedel-Heller S, von Gottberg C, Kilian R. The psychometric properties of the German version of the WHOQOL-OLD in the German population aged 60 and older. Health and Quality of Life Outcomes. 2014;12:105. doi: 10.1186/s12955-014-0105-4. - DOI - PMC - PubMed