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. 2020 Jan 27:53:e20180533.
doi: 10.1590/0037-8682-0533-2018. eCollection 2020.

Hepatitis B: Prevalence and occult infection in HIV-infected patients

Samira Julien Calux  1 , Vanessa Cristina Martins Silva  1 , Adriana Parise Compri  1 , Marcílio Figueiredo Lemos  1 , Ana Paula de Torres Santos  2 , Isabel Takano Oba  1 , Maria Cássia J Mendes-Correa  3 , Regina Célia Moreira  1
Affiliations

Hepatitis B: Prevalence and occult infection in HIV-infected patients

Samira Julien Calux et al. Rev Soc Bras Med Trop. .

Abstract

Introduction: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection.

Methods: All samples were tested for serology markers and using qPCR.

Results: This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI.

Conclusions: We observed a high prevalence of HBV among HIV patients. In addition, the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology.

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Conflict of interest statement

Conflict of Interest: The authors declare that there is no conflict of interest.

References

    1. World Health Organization (WHO) Fact Sheet 204. 2018. [17.Oct.2018]. Available from: http://www.who.int/mediacentre/factsheets/fs204/en/index.html.
    1. World Health Organization (WHO) HIV and hepatitis co-infections. 2018. [17.Oct.2018]. Available from: http://www.who.int/hiv/topics/hepatitis/hepatitisinfo/en/
    1. Li Y, Wang H, Li T. Hepatitis B virus/human immunodeficiency virus coinfection: interaction among human immunodeficiency virus infection, chronic hepatitis B virus infection, and host immunity. Chin Med J. 2012;125(13):2371–2377. - PubMed
    1. Thio C, Smeaton L, Saulynas M, Hwang H, Saravan S, Kulkarni S, et al. Characterization of HIV-HBV co-infection in a multi-national HIV infected cohort. AIDS. 2013;27(2):191–201. - PMC - PubMed
    1. Souza M, Passos A, Machado A, Figueiredo J, Esmeraldino L. HIV and hepatitis B virus co-infection: prevalence and risk factors. Rev Soc Bras Med Trop. 2004;37(5):391–395. - PubMed